Cystic Fibrosis Defective Response to Infection Involves Autophagy and Lipid Metabolism

Cystic fibrosis (CF) is a hereditary disease, with 70% of patients developing a proteinopathy related to the deletion of phenylalanine 508. CF is associated with multiple organ dysfunction, chronic inflammation, and recurrent lung infections. CF is characterized by defective autophagy, lipid metabol...

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Detalhes bibliográficos
Main Authors: Alessandra Mingione, Emerenziana Ottaviano, Matteo Barcella, Ivan Merelli, Lorenzo Rosso, Tatiana Armeni, Natalia Cirilli, Riccardo Ghidoni, Elisa Borghi, Paola Signorelli
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-08-01
Colecção:Cells
Assuntos:
cystic fibrosis
sphingolipids
autophagy
myriocin
<i>Aspergillus fumigatus</i>
Acesso em linha:https://www.mdpi.com/2073-4409/9/8/1845
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