Development of a Novel Methotrexate-Loaded Nanoemulsion for Rheumatoid Arthritis Treatment with Site-Specific Targeting Subcutaneous Delivery

Rheumatoid arthritis (RA) is a systemic, chronic autoimmune disease that causes disability due to progressive inflammation and destruction of the tissues around the joints. Methotrexate is mainly used to prevent the progression of joint destruction and reduce the deformity. The major challenge in tr...

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Main Authors: Parvathy Suresh, Mounir M. Salem-Bekhit, Hafsa Palathum Veedu, Sultan Alshehri, Sreeja Chandrasekhar Nair, Sarah I. Bukhari, Vidya Viswanad, Ehab I. Taha, Ram Kumar Sahu, Mohammed M. Ghoneim, Ibrahim Elbagory
格式: Artigo
語言:Inglês
出版: MDPI AG 2022-04-01
叢編:Nanomaterials
主題:
rheumatoid arthritis
methotrexate
anti-arthritic activity
nanoemulsion
hemocompatibility
MTT assay
在線閱讀:https://www.mdpi.com/2079-4991/12/8/1299
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