Biological molecular layer classification of muscle-invasive bladder cancer opens new treatment opportunities

Abstract Background Muscle-invasive bladder tumors are associated with a high risk of relapse and metastasis even after neoadjuvant chemotherapy and radical cystectomy. Therefore, further therapeutic options are needed and molecular characterization of the disease may help to identify new targets. T...

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Auteurs principaux: Lucía Trilla-Fuertes, Angelo Gámez-Pozo, Guillermo Prado-Vázquez, Andrea Zapater-Moros, Mariana Díaz-Almirón, Jorge M. Arevalillo, María Ferrer-Gómez, Hilario Navarro, Paloma Maín, Enrique Espinosa, Álvaro Pinto, Juan Ángel Fresno Vara
Format: Artigo
Langue:Inglês
Publié: BMC 2019-06-01
Collection:BMC Cancer
Sujets:
Muscle-invasive bladder cancer
Molecular subtypes
Personalized medicine
Androgen receptor
Immune status
Accès en ligne:http://link.springer.com/article/10.1186/s12885-019-5858-z
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