Improvement in the dissolution rate and tableting properties of cefuroxime axetil by melt-granulated dispersion and surface adsorption

A combination of melt-granulated dispersion and surface adsorption techniques was used to enhance the dissolution and tableting properties of cefuroxime axetil (CA). Gelucire 50/13 was used as the melt-dispersion carrier and Sylysia 350 was used to adsorb the melt dispersion. Solubility studies show...

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Hlavní autoři: Jammula Sruti, Chinam Niranjan Patra, Suryakanta Swain, Kanhu Charan Panigrahi, Allupati Premananda Patro, Sarwar Beg, Subas Chandra Dinda, Muddana Eswara Bhanoji Rao
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2013-04-01
Edice:Acta Pharmaceutica Sinica B
Témata:
Molecular modeling
Gelucire 50/13
Sylysia 350
Microbiological assay
Rapidly dissolving tablet
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2211383513000130
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