Improvement in the dissolution rate and tableting properties of cefuroxime axetil by melt-granulated dispersion and surface adsorption

A combination of melt-granulated dispersion and surface adsorption techniques was used to enhance the dissolution and tableting properties of cefuroxime axetil (CA). Gelucire 50/13 was used as the melt-dispersion carrier and Sylysia 350 was used to adsorb the melt dispersion. Solubility studies show...

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Main Authors: Jammula Sruti, Chinam Niranjan Patra, Suryakanta Swain, Kanhu Charan Panigrahi, Allupati Premananda Patro, Sarwar Beg, Subas Chandra Dinda, Muddana Eswara Bhanoji Rao
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013-04-01
Colecção:Acta Pharmaceutica Sinica B
Assuntos:
Molecular modeling
Gelucire 50/13
Sylysia 350
Microbiological assay
Rapidly dissolving tablet
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211383513000130
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