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Imatinib Mesylate: Past Successes and Future Challenges in the Treatment of Gastrointestinal Stromal Tumors
Just over a decade ago, gastrointestinal tumours were a poorly understood mesenchymal neoplasm unsuccessfully treated with chemotherapy. Cytotoxic therapy for advanced disease yielded response rates of 10% and median survival of just 18 months. However, the discovery of KIT and platelet derived grow...
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Autor principal: | |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE Publishing
2011-01-01
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Colecção: | Clinical Medicine Insights: Oncology |
Acesso em linha: | https://doi.org/10.4137/CMO.S4259 |
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