Tumor Angiogenic Inhibition Triggered Necrosis (TAITN) in Oral Cancer

CXCR4 is a chemokine receptor crucial in tumor progression, although the angiogenic role of CXCR4 in oral squamous cell carcinoma (OSCC) has not been investigated. Here we show that CXCR4 is crucial for tumor angiogenesis, thereby supporting tumor survival in OSCC. Immunohistochemistry on human clin...

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Detalhes bibliográficos
Main Authors: Saori Yoshida, Hotaka Kawai, Takanori Eguchi, Shintaro Sukegawa, May Wathone Oo, Chang Anqi, Kiyofumi Takabatake, Keisuke Nakano, Kuniaki Okamoto, Hitoshi Nagatsuka
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-07-01
Colecção:Cells
Assuntos:
tumor blood vessel
tumor angiogenic inhibition triggered necrosis (TAITN)
CXCR4 antagonist
oral squamous cell carcinoma
hypoxia
Acesso em linha:https://www.mdpi.com/2073-4409/8/7/761
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