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Expression Profile of Sonic Hedgehog Pathway Members in the Developing Human Fetal Brain

The Sonic Hedgehog (SHH) pathway plays a central role in the developing mammalian CNS. In our study, we aimed to investigate the spatiotemporal SHH pathway expression pattern in human fetal brains. We analyzed 22 normal fetal brains for Shh, Patched, Smoothened, and Gli1-3 expression by immunohistoc...

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Bibliografiske detaljer
Main Authors: Julia Tichy, Jenny Zinke, Benedikt Bunz, Richard Meyermann, Patrick N. Harter, Michel Mittelbronn
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Limited 2015-01-01
Serier:BioMed Research International
Online adgang:http://dx.doi.org/10.1155/2015/494269
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