Using patient-centered end-points in older adults participating in clinical trials

Conventional end-points, primarily based on the pharmacodynamic effects of a specific drug, are used to assess the efficacy of pharmacological treatment in clinical trials. However, their application and interpretation in complex frail older patients, a patient group with high inter-individual varia...

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Autori principali: Arduino A. Mangoni, Kimberley Ruxton
Natura: Artigo
Lingua:Inglês
Pubblicazione: PAGEPress Publications 2016-04-01
Serie:Geriatric Care
Soggetti:
Clinical trials
end-points
old age
drug development
frailty.
Accesso online:http://www.pagepressjournals.org/index.php/gc/article/view/5893
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