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Mechanical loading of isolated cardiac muscle with a real‐time computed Windkessel model of the vasculature impedance

Abstract To date, the mechanical loads imposed on isolated cardiac muscle tissue in vitro have been oversimplified. Researchers typically applied loads that are time‐invariant, resulting in either isometric and auxotonic contractions, or flat‐topped (isotonic shortening) work‐loops. These contractio...

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Autori principali: Amy S. Garrett, Toan Pham, Denis Loiselle, June‐Chiew Han, Andrew Taberner
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2019-09-01
Serie:Physiological Reports
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Accesso online:https://doi.org/10.14814/phy2.14184
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