Wistar rats resistant to the hypertensive effects of ouabain exhibit enhanced cardiac vagal activity and elevated plasma levels of calcitonin gene-related peptide.

Ouabain is a cardiac glycoside produced in the adrenal glands and hypothalamus. It affects the function of all cells by binding to Na+/K+-ATPase. Several lines of evidence suggest that endogenous ouabain could be involved in the pathogenesis of essential (particularly, salt-sensitive) hypertension....

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Главные авторы: Elham Ghadhanfar, Maie Al-Bader, Marian Turcani
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2014-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC4184851?pdf=render
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