Social isolation triggers oxidative status and impairs systemic and hepatic insulin sensitivity in normoglycemic rats

Drug-naïve psychotic patients show metabolic and hepatic dysfunctions. The rat social isolation model of psychosis allows to investigate mechanisms leading to these disturbances to which oxidative stress crucially contributes. Here, we investigated isolation-induced central and peripheral dysfunctio...

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Main Authors: Maria Bove, Adriano Lama, Stefania Schiavone, Claudio Pirozzi, Paolo Tucci, Vladyslav Sikora, Giovanna Trinchese, Gaetano Corso, Maria Grazia Morgese, Luigia Trabace
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2022-05-01
Sraith:Biomedicine & Pharmacotherapy
Ábhair:
Insulin
Social isolation
Oxidative stress
Liver
Hypothalamus
Rochtain Ar Líne:http://www.sciencedirect.com/science/article/pii/S0753332222002086
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