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Differential Influence of Sample Sex and Neuronal Maturation on mRNA and Protein Transport in Induced Human Neurons

Nucleocytoplasmic transport (NCT) across thenuclear envelope (NE) is tightly regulated in eukaryotic cells and iscritical for maintaining cellular homeostasis. Its dysregulationleads to aging and neurodegeneration. Because they maintainaging-associated hallmarks, directly reprogrammed neurons from h...

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Detalhes bibliográficos
Main Authors: Baojin Ding, Masuma Akter, Chun-Li Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-04-01
Colecção:Frontiers in Molecular Neuroscience
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fnmol.2020.00046/full
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