Positron Emission Tomography Molecular Imaging Biomarkers for Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with limited treatment options. Despite decades of therapeutic development, only two modestly efficacious disease-modifying drugs—riluzole and edaravone—are available to ALS patients. Biomarkers that can facilitate ALS diagnos...

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Bibliographic Details
Main Authors: Sheena Chew, Nazem Atassi
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Neurology
Subjects:
amyotrophic lateral sclerosis
neuroimaging
positron emission tomography
biomarker
diagnostic biomarker
pharmacodynamic biomarker
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00135/full
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