Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies

Gene expression dictates fundamental cellular processes and its de-regulation leads to pathological conditions. A key contributor to the fine-tuning of gene expression is Dicer, an RNA-binding protein (RBPs) that forms complexes and affects transcription by acting at the post-transcriptional level v...

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Hlavní autoři: Eleni I. Theotoki, Vasiliki I. Pantazopoulou, Stella Georgiou, Panos Kakoulidis, Vicky Filippa, Dimitrios J. Stravopodis, Ema Anastasiadou
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2020-09-01
Edice:International Journal of Molecular Sciences
Témata:
Dicer ribonuclease
post-transcriptional regulation
RNA binding proteins
microRNAs
RISC
Dicer1 syndrome
On-line přístup:https://www.mdpi.com/1422-0067/21/19/7223
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