Drug Use in Denmark for Drugs Having Pharmacogenomics (PGx) Based Dosing Guidelines from CPIC or DPWG for CYP2D6 and CYP2C19 Drug–Gene Pairs: Perspectives for Introducing PGx Test to Polypharmacy Patients

Background: The cytochrome P450 drug metabolizing enzymes CYP2D6 and CYP2C19 are the major targets for pharmacogenomics (PGx) testing and determining for drug response. Clinical dosing guidelines for specific drug-gene interactions (DGI) are publicly available through PharmGKB. The aim of this regis...

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Hlavní autoři: Niels Westergaard, Regitze Søgaard Nielsen, Steffen Jørgensen, Charlotte Vermehren
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2020-01-01
Edice:Journal of Personalized Medicine
Témata:
drug consumption
pharmacogenomics
cytochrome p450
polypharmacy
pharmacogenomics testing
drug-drug interactions
drug–gene interaction
On-line přístup:https://www.mdpi.com/2075-4426/10/1/3
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