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Upregulating Human Cathelicidin Antimicrobial Peptide LL-37 Expression May Prevent Severe COVID-19 Inflammatory Responses and Reduce Microthrombosis

COVID-19 is characterized by hyperactivation by inflammatory cytokines and recruitment of macrophages, neutrophils, and other immune cells, all hallmarks of a strong inflammatory response that can lead to severe complications and multi-organ damage. Mortality in COVID-19 patients is associated with...

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Main Authors: Karim M. Aloul, Josefine Eilsø Nielsen, Erwin B. Defensor, Jennifer S. Lin, John A. Fortkort, Mehrdad Shamloo, Jeffrey D. Cirillo, Adrian F. Gombart, Annelise E. Barron
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Immunology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.880961/full
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