PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens.

ΔFosB is a stable transcription factor which accumulates in the nucleus accumbens (NAc), a key part of the brain's reward circuitry, in response to chronic exposure to cocaine or other drugs of abuse. While ΔFosB is known to heterodimerize with a Jun family member to form an active transcriptio...

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Autores principales: Yoko H Ohnishi, Yoshinori N Ohnishi, Takanori Nakamura, Mizuki Ohno, Pamela J Kennedy, Yasuyuki Ohkawa, Akinori Nishi, Rachael Neve, Teruhisa Tsuzuki, Eric J Nestler
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2015-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC4427335?pdf=render
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