GII.4 Human Norovirus: Surveying the Antigenic Landscape

Human norovirus is the leading cause of viral acute onset gastroenteritis disease burden, with 685 million infections reported annually. Vulnerable populations, such as children under the age of 5 years, the immunocompromised, and the elderly show a need for inducible immunity, as symptomatic dehydr...

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Bibliographic Details
Main Authors: Michael L. Mallory, Lisa C. Lindesmith, Rachel L. Graham, Ralph S. Baric
Format: Artigo
Language:Inglês
Published: MDPI AG 2019-02-01
Series:Viruses
Subjects:
norovirus
antigenic landscape
blockade antibodies
neutralizing antibodies
epitope
antigenic drift
evolution
Online Access:https://www.mdpi.com/1999-4915/11/2/177
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