Realization of Robust and Precise Regulation of Gene Expression by Multiple Sigma Recognizable Artificial Promoters

Precise regulation of gene expression is fundamental for tailor-made gene circuit design in synthetic biology. Current strategies for this type of development are mainly based on directed evolution beginning with a native promoter template. The performances of engineered promoters are usually limite...

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Main Authors: Laichuang Han, Qiaoqing Chen, Qiao Lin, Jintao Cheng, Li Zhou, Zhongmei Liu, Junling Guo, Linpei Zhang, Wenjing Cui, Zhemin Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-02-01
Colecção:Frontiers in Bioengineering and Biotechnology
Assuntos:
Bacillus subtilis
promoter engineering
hybrid promoter
gene expression
sigma factors
Acesso em linha:https://www.frontiersin.org/article/10.3389/fbioe.2020.00092/full
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