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Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression

Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle degeneration due to dystrophin gene mutations. Patients with DMD initially experience muscle weakness in their limbs during adolescence. With age, patients develop fatal respiratory and cardiac dysfunctions....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Min Ho Song, Jimeen Yoo, Jae Gyun Oh, Hyun Kook, Woo Jin Park, Dongtak Jeong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2022-04-01
Cyfres:Frontiers in Cardiovascular Medicine
Pynciau:
DMD
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fcvm.2022.763544/full
Tagiau: Ychwanegu Tag
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