Mechanistic basis and clinical relevance of the role of transforming growth factor-β in cancer

Transforming growth factor-β (TGF-β) is a key factor in cancer development and progression. TGF-β can suppress tumorigenesis by inhibiting cell cycle progression and stimulating apoptosis in early stages of cancer progression. However, TGF-β can modulate cancer-related processes, such as cell invasi...

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Huvudupphovsmän: Run-Long Lin, Lu-Jun Zhao
Materialtyp: Artigo
Språk:Inglês
Publicerad: China Anti-Cancer Association 2015-12-01
Serie:Cancer Biology & Medicine
Ämnen:
Transforming growth factor-β (TGF-β)
neoplasms
prognosis
therapeutics
Länkar:http://www.cancerbiomed.org/index.php/cocr/article/view/892
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