Curcumin inhibits CD4(+) T cell activation, but augments CD69 expression and TGF-β1-mediated generation of regulatory T cells at late phase.

BACKGROUND: Curcumin is a promising candidate for a natural medicinal agent to treat chronic inflammatory diseases. Although CD4(+) T cells have been implicated in the pathogenesis of chronic inflammation, whether curcumin directly regulates CD4(+) T cells has not been definitively established. Here...

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Bibliographic Details
Main Authors: Girak Kim, Mi Seon Jang, Young Min Son, Min Ji Seo, Sang Yun Ji, Seung Hyun Han, In Duk Jung, Yeong-Min Park, Hyun Jung Jung, Cheol-Heui Yun
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3637266?pdf=render
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