Instrumental Role of Helicobacter pylori γ-Glutamyl Transpeptidase in VacA-Dependent Vacuolation in Gastric Epithelial Cells.

Helicobacter pylori causes cellular vacuolation in host cells, a cytotoxic event attributed to vacuolating cytotoxin (VacA) and the presence of permeant weak bases such as ammonia. We report here the role of γ-glutamyl transpeptidase (GGT), a constitutively expressed secretory enzyme of H. pylori, i...

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Detaylı Bibliyografya
Asıl Yazarlar: Samantha Shi Min Ling, Lawrence Han Boon Khoo, Le-Ann Hwang, Khay Guan Yeoh, Bow Ho
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2015-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC4482420?pdf=render
Etiketler: Etiketle
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