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Metabolic Activation and Carcinogenesis of Tobacco-Specific Nitrosamine N’-Nitrosonornicotine (NNN): A Density Function Theory and Molecular Docking Study

N’-nitrosonornicotine (NNN) is one of the tobacco-specific nitrosamines (TSNAs) that exists widely in smoke and smokeless tobacco products. NNN can induce tumors in various laboratory animal models and has been identified by International Agency for Research on Cancer (IARC) as a human car...

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Main Authors: Tengjiao Fan, Guohui Sun, Lijiao Zhao, Xin Cui, Rugang Zhong
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2019-01-01
Serija:International Journal of Environmental Research and Public Health
Teme:
Online dostop:http://www.mdpi.com/1660-4601/16/2/178
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