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Average rank-based score to measure deregulation of molecular pathway gene sets.

BACKGROUND: Deregulation of biological pathways has been shown to be involved in the turmorigenesis of a variety of cancers. The co-regulation of pathways in tumor and normal tissues has not been studied in a systematic manner. RESULTS: In this study we propose a novel statistic named AR-score (aver...

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Detalhes bibliográficos
Main Authors: Huan Yang, Chao Cheng, Wei Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3212578?pdf=render
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