Boosting the Brain Delivery of Atazanavir through Nanostructured Lipid Carrier-Based Approach for Mitigating NeuroAIDS

Atazanavir (ATZ) presents poor brain availability when administered orally, which poses a major hurdle in its use as an effective therapy for the management of NeuroAIDS. The utilization of nanostructured lipid carriers (NLCs) in conjunction with the premeditated use of excipients can be a potential...

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Main Authors: Saif Ahmad Khan, Saleha Rehman, Bushra Nabi, Ashif Iqubal, Nida Nehal, Usama A. Fahmy, Sabna Kotta, Sanjula Baboota, Shadab Md, Javed Ali
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2020-11-01
Serija:Pharmaceutics
Teme:
atazanavir
nanostructured lipid carriers
neuroAIDS
brain targeting
histopathology
Online dostop:https://www.mdpi.com/1999-4923/12/11/1059
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