Boosting the Brain Delivery of Atazanavir through Nanostructured Lipid Carrier-Based Approach for Mitigating NeuroAIDS

Atazanavir (ATZ) presents poor brain availability when administered orally, which poses a major hurdle in its use as an effective therapy for the management of NeuroAIDS. The utilization of nanostructured lipid carriers (NLCs) in conjunction with the premeditated use of excipients can be a potential...

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Detalhes bibliográficos
Main Authors: Saif Ahmad Khan, Saleha Rehman, Bushra Nabi, Ashif Iqubal, Nida Nehal, Usama A. Fahmy, Sabna Kotta, Sanjula Baboota, Shadab Md, Javed Ali
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-11-01
Colecção:Pharmaceutics
Assuntos:
atazanavir
nanostructured lipid carriers
neuroAIDS
brain targeting
histopathology
Acesso em linha:https://www.mdpi.com/1999-4923/12/11/1059
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