Pathogen Evasion of Chemokine Response Through Suppression of CXCL10

Clearance of intracellular pathogens, such as Leishmania (L.) major, depends on an immune response with well-regulated cytokine signaling. Here we describe a pathogen-mediated mechanism of evading CXCL10, a chemokine with diverse antimicrobial functions, including T cell recruitment. Infection with...

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Autori principali: Alejandro L. Antonia, Kyle D. Gibbs, Esme D. Trahair, Kelly J. Pittman, Amelia T. Martin, Benjamin H. Schott, Jeffrey S. Smith, Sudarshan Rajagopal, J. Will Thompson, Richard Lee Reinhardt, Dennis C. Ko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019-08-01
Serie:Frontiers in Cellular and Infection Microbiology
Soggetti:
CXCL10
CXCR3
Leishmania
gp63
leishmanolysin
Chlamydia
Accesso online:https://www.frontiersin.org/article/10.3389/fcimb.2019.00280/full
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