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An epigenetic association analysis of childhood trauma in psychosis reveals possible overlap with methylation changes associated with PTSD

Abstract Patients with a severe mental disorder report significantly higher levels of childhood trauma (CT) than healthy individuals. Studies have suggested that CT may affect brain plasticity through epigenetic mechanisms and contribute to developing various psychiatric disorders. We performed a bl...

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Main Authors: Solveig Løkhammer, Anne-Kristin Stavrum, Tatiana Polushina, Monica Aas, Akiah A. Ottesen, Ole A. Andreassen, Ingrid Melle, Stephanie Le Hellard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2022-04-01
Colecção:Translational Psychiatry
Acesso em linha:https://doi.org/10.1038/s41398-022-01936-8
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