Role of complement factor B rs4151667 (L9H) polymorphisms and its interactional role with CFH Y402H and C3 rs2230199 (R102G) risk variants in age-related macular degeneration: a case control study

Abstract Background Age-related Macular Degeneration (AMD) is a complex eye disease, which is genetically associated with different susceptibility loci. We planned to investigate the possible association of Complement Factor B (CFB) rs4151667 (L9H) variants and their possible interaction with Comple...

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Main Authors: Nasrin Roshanipour, Maryam Ghaffari Laleh, Mortaza Bonyadi, Mohammad Hossein Jabbarpoor Bonyadi, Masoud Soheilian, Alireza Javadzadeh, Mehdi Yaseri
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMC 2020-08-01
Sraith:BMC Ophthalmology
Ábhair:
Age-related macular degeneration (AMD)
Complement factor B (CFB) gene
Complement factor H (CFH) gene
Complement factor 3 (C3) gene
L9H polymorphisms
Y402H polymorphism
Rochtain Ar Líne:http://link.springer.com/article/10.1186/s12886-020-01552-4
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