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Genetic manipulation of Leishmania donovani threonyl tRNA synthetase facilitates its exploration as a potential therapeutic target.

Aminoacyl tRNA synthetases are central enzymes required for protein synthesis. These enzymes are the known drug targets in bacteria and fungi. Here, we for the first time report the functional characterization of threonyl tRNA synthetase (LdThrRS) of Leishmania donovani, a protozoan parasite, the pr...

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Detalhes bibliográficos
Main Authors: Sanya Chadha, Ramachandran Vijayan, Sakshi Gupta, Manoj Munde, Samudrala Gourinath, Rentala Madhubala
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2018-06-01
Colecção:PLoS Neglected Tropical Diseases
Acesso em linha:http://europepmc.org/articles/PMC6025875?pdf=render
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