BCG and BCG/DNAhsp65 Vaccinations Promote Protective Effects without Deleterious Consequences for Experimental Autoimmune Encephalomyelitis

A prime-boost strategy conserving BCG is considered the most promising vaccine to control tuberculosis. A boost with a DNA vaccine containing the mycobacterial gene of a heat shock protein (pVAXhsp65) after BCG priming protected mice against experimental tuberculosis. However, anti-hsp65 immunity co...

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Main Authors: Sofia Fernanda Gonçalves Zorzella-Pezavento, Clara Pires Fujiara Guerino, Fernanda Chiuso-Minicucci, Thais Graziela Donegá França, Larissa Lumi Watanabe Ishikawa, Ana Paula Masson, Célio Lopes Silva, Alexandrina Sartori
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Limited 2013-01-01
Series:Clinical and Developmental Immunology
Acceso en liña:http://dx.doi.org/10.1155/2013/721383
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