Acute Stress Facilitates LTD Induction at Glutamatergic Synapses in the Hippocampal CA1 Region by Activating μ-Opioid Receptors on GABAergic Neurons

Acute stress impairs recall memory through the facilitation of long-term depression (LTD) of hippocampal synaptic transmission. The endogenous opioid system (EOS) plays essential roles in stress-related emotional and physiological responses. Specifically, behavioral studies have shown that the impai...

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Main Authors: Ka-Min Fan, Li-Juan Qiu, Ning Ma, Yi-Nan Du, Zhao-Qiang Qian, Chun-Ling Wei, Jing Han, Wei Ren, Mei-Mei Shi, Zhi-Qiang Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-02-01
Colecção:Frontiers in Neuroscience
Assuntos:
synaptic plasticity
hippocampus
endogenous opioid system
acute stress
inhibitory transmission
μ-opioid receptors
Acesso em linha:https://www.frontiersin.org/article/10.3389/fnins.2019.00071/full
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