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The Organophosphate Paraoxon and Its Antidote Obidoxime Inhibit Thrombin Activity and Affect Coagulation In Vitro.

Organophosphates (OPs) are potentially able to affect serine proteases by reacting with their active site. The potential effects of OPs on coagulation factors such as thrombin and on coagulation tests have been only partially characterized and potential interactions with OPs antidotes such as oximes...

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Bibliografski detalji
Glavni autori: Valery Golderman, Efrat Shavit-Stein, Ilia Tamarin, Yossi Rosman, Shai Shrot, Nurit Rosenberg, Nicola Maggio, Joab Chapman, Arik Eisenkraft
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2016-01-01
Serija:PLoS ONE
Online pristup:http://europepmc.org/articles/PMC5045196?pdf=render
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