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Role of genes GSTM1, GSTT1, and MnSOD in the development of late-onset Alzheimer disease and their relationship with APOE*4

Introduction: Several studies have reported increased oxidation of lipids, proteins and DNA in the brains of patients with Alzheimer disease (AD). Moreover, these patients display differences in the activity and polymorphisms of the genes encoding the enzymes GST (T1, M1) and MnSOD. For these reason...

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Main Authors: E. de Mendonça, E. Salazar Alcalá, M. Fernández-Mestre
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier España 2016-10-01
Colecção:Neurología (English Edition)
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2173580816300888
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