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PDE2 is a novel target for attenuating tumor formation in a mouse model of UVB-induced skin carcinogenesis.
Our previous studies demonstrated that the topical application of caffeine is a potent inhibitor of UVB-induced carcinogenesis and selectively increases apoptosis in tumors but not in non-tumor areas of the epidermis in mice that are at a high risk for developing skin cancer. While this effect is ma...
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| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2014-01-01
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| Serija: | PLoS ONE |
| Online dostop: | http://europepmc.org/articles/PMC4199678?pdf=render |
| Oznake: |
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