Asp305Gly mutation improved the activity and stability of the styrene monooxygenase for efficient epoxide production in Pseudomonas putida KT2440

Abstract Background Styrene monooxygenase (SMO) catalyzes the first step of aromatic alkene degradation yielding the corresponding epoxides. Because of its broad spectrum of substrates, the enzyme harbors a great potential for an application in medicine and chemical industries. Results In this study...

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Main Authors: Chunlin Tan, Xian Zhang, Zhijing Zhu, Meijuan Xu, Taowei Yang, Tolbert Osire, Shangtian Yang, Zhiming Rao
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2019-01-01
Series:Microbial Cell Factories
Assuntos:
Styrene monooxygenase
Biocatalysis
Site-saturation mutagenesis
Epoxide
Acceso en liña:http://link.springer.com/article/10.1186/s12934-019-1065-5
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