NEAT1 is Required for the Expression of the Liver Cancer Stem Cell Marker CD44

CD44, a cancer stem cell (CSC) marker, is required for maintaining CSC properties in hepatocellular carcinoma (HCC). Nuclear enriched abundant transcript 1 (NEAT1), a long noncoding RNA (lncRNA), is an oncogenic driver in HCC. In the present study, we investigated the significance of the <i>NE...

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Detalhes bibliográficos
Main Authors: Shigemi Koyama, Hiroyuki Tsuchiya, Masataka Amisaki, Hiromi Sakaguchi, Soichiro Honjo, Yoshiyuki Fujiwara, Goshi Shiota
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-03-01
Colecção:International Journal of Molecular Sciences
Assuntos:
cancer stem cells
neat1
hepatocellular carcinoma
cd44
spheroid
Acesso em linha:https://www.mdpi.com/1422-0067/21/6/1927
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