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The Protective Effect of Beraprost Sodium on Diabetic Nephropathy by Inhibiting Inflammation and p38 MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Rats

Background. p38 mitogen-activated protein kinase (MAPK) plays a crucial role in regulating signaling pathways implicated in inflammatory processes leading to diabetic nephropathy (DN). This study aimed to examine p38 MAPK activation in DN and determine whether beraprost sodium (BPS) ameliorates DN b...

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Detalhes bibliográficos
Main Authors: Li Peng, Jie Li, Yixing Xu, Yangtian Wang, Hong Du, Jiaqing Shao, Zhimin Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2016-01-01
Colecção:International Journal of Endocrinology
Acesso em linha:http://dx.doi.org/10.1155/2016/1690474
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