Deficient mismatch repair and RAS mutation in colorectal carcinoma patients: a retrospective study in Eastern China

Objectives To investigate the frequency and prognostic role of deficient mismatch repair (dMMR) and RAS mutation in Chinese patients with colorectal carcinoma. Methods Clinical and pathological information from 813 patients were reviewed and recorded. Expression of mismatch repair proteins was teste...

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Detalhes bibliográficos
Main Authors: Xiangyan Zhang, Wenwen Ran, Jie Wu, Hong Li, Huamin Liu, Lili Wang, Yujing Xiao, Xiaonan Wang, Yujun Li, Xiaoming Xing
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2018-02-01
Colecção:PeerJ
Assuntos:
KRAS mutation
Deficient mismatch repair (dMMR )
NRAS mutation
Prognosis
Clinicopathological characteristics
Colorectal carcinoma
Acesso em linha:https://peerj.com/articles/4341.pdf
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