Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury

Abstract Background Preterm newborns are at high risk of developing neurodevelopmental deficits caused by neuroinflammation leading to perinatal brain injury. Human Wharton’s jelly mesenchymal stem cells (hWJ-MSC) derived from the umbilical cord have been suggested to reduce neuroinflammation, in pa...

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Detalhes bibliográficos
Main Authors: Gierin Thomi, Daniel Surbek, Valérie Haesler, Marianne Joerger-Messerli, Andreina Schoeberlein
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-03-01
Colecção:Stem Cell Research & Therapy
Assuntos:
Preterm birth
Perinatal brain damage
White matter injury
Neuroinflammation
Hypoxia-ischemia
Mesenchymal stem cells
Acesso em linha:http://link.springer.com/article/10.1186/s13287-019-1207-z
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