SDF-1α Reduces Human Natural Killer Cell Cytotoxicity against Chronic Myelogenous Leukemia K562 Cells

Stromal cell-derived factor-1 alpha (SDF-1α) has been shown to be up-regulated in a variety of malignancies. So that, its expression is associated with poor prognosis and invasiveness. Natural killer (NK) cells are important effector cells against virus-infected and transformed cells. Especially the...

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Main Authors: Alireza Mardomi, Hadi Hossein-Nataj, Narjes Jafari, Nabiallah Mohammadi, Saeid Abediankenari
Formato: Artigo
Idioma:Inglês
Publicado em: Tehran University of Medical Sciences 2019-10-01
Colecção:Iranian Journal of Allergy, Asthma and Immunology
Assuntos:
Immunologic cytotoxicity
Killer cells
Natural
NKG2D
SDF-1α
Acesso em linha:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2265
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