L1CAM Is a Marker for Enriching Corticospinal Motor Neurons in the Developing Brain

The cerebral cortical tissue of murine embryo and pluripotent stem cell-derived neurons can survive in the adult brain and extend axons to the spinal cord. These features suggest that cell transplantation can be a strategy to reconstruct the corticospinal tract (CST). It is unknown, however, which c...

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Detalhes bibliográficos
Main Authors: Bumpei Samata, Rika Takaichi, Yuko Ishii, Kaori Fukushima, Harumi Nakagawa, Yuichi Ono, Jun Takahashi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-02-01
Colecção:Frontiers in Cellular Neuroscience
Assuntos:
L1 cell adhesion molecule
corticospinal motor neurons
transplantation
corticospinal tract
cell sorting
Acesso em linha:https://www.frontiersin.org/article/10.3389/fncel.2020.00031/full
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