Bio-Inspired Amphiphilic Block-Copolymers Based on Synthetic Glycopolymer and Poly(Amino Acid) as Potential Drug Delivery Systems

In this work, a method to prepare hybrid amphiphilic block copolymers consisting of biocompatible synthetic glycopolymer with non-degradable backbone and biodegradable poly(amino acid) (PAA) was developed. The glycopolymer, poly(2-deoxy-2-methacrylamido-D-glucose) (PMAG), was synthesized via reversi...

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Detalhes bibliográficos
Main Authors: Mariia Levit, Natalia Zashikhina, Alena Vdovchenko, Anatoliy Dobrodumov, Natalya Zakharova, Anna Kashina, Eckart Rühl, Antonina Lavrentieva, Thomas Scheper, Tatiana Tennikova, Evgenia Korzhikova-Vlakh
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-01-01
Colecção:Polymers
Assuntos:
synthetic glycopolymers
poly(amino acids)
amphiphilic block copolymers
modification of terminal groups
nanoparticles
redox-responsive systems
paclitaxel
drug delivery systems
Acesso em linha:https://www.mdpi.com/2073-4360/12/1/183
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