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Lack of Transcription Triggers H3K27me3 Accumulation in the Gene Body
Trimethylated H3K27 (H3K27me3) is associated with transcriptional repression, and its abundance in chromatin is frequently altered in cancer. However, it has remained unclear how genomic regions modified by H3K27me3 are specified and formed. We previously showed that downregulation of transcription...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2016-07-01
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Colecção: | Cell Reports |
Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2211124716307744 |
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