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Lack of Transcription Triggers H3K27me3 Accumulation in the Gene Body

Trimethylated H3K27 (H3K27me3) is associated with transcriptional repression, and its abundance in chromatin is frequently altered in cancer. However, it has remained unclear how genomic regions modified by H3K27me3 are specified and formed. We previously showed that downregulation of transcription...

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Detalhes bibliográficos
Main Authors: Masaki Hosogane, Ryo Funayama, Matsuyuki Shirota, Keiko Nakayama
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016-07-01
Colecção:Cell Reports
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124716307744
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