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Prokaryotic expression and characterization of the heterodimeric construction of ZnT8 and its application for autoantibodies detection in diabetes mellitus

Abstract Background In the present work we described the recombinant production and characterization of heterodimeric construction ZnT8-Arg-Trp325 fused to thioredoxin using a high-performance expression system such as Escherichia coli. In addition, we apply this novel recombinant antigen in a non-r...

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Main Authors: Natalia I. Faccinetti, Luciano L. Guerra, Adriana V. Sabljic, Silvina S. Bombicino, Bruno D. Rovitto, Ruben F. Iacono, Edgardo Poskus, Aldana Trabucchi, Silvina N. Valdez
格式: Artigo
語言:Inglês
出版: BMC 2017-11-01
叢編:Microbial Cell Factories
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在線閱讀:http://link.springer.com/article/10.1186/s12934-017-0816-4
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