Prokaryotic expression and characterization of the heterodimeric construction of ZnT8 and its application for autoantibodies detection in diabetes mellitus

Abstract Background In the present work we described the recombinant production and characterization of heterodimeric construction ZnT8-Arg-Trp325 fused to thioredoxin using a high-performance expression system such as Escherichia coli. In addition, we apply this novel recombinant antigen in a non-r...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Natalia I. Faccinetti, Luciano L. Guerra, Adriana V. Sabljic, Silvina S. Bombicino, Bruno D. Rovitto, Ruben F. Iacono, Edgardo Poskus, Aldana Trabucchi, Silvina N. Valdez
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2017-11-01
Sarja:Microbial Cell Factories
Aiheet:
Diabetes mellitus
ZnT8
Autoantibody
Recombinant protein expression
Immunoassays
Escherichia coli
Linkit:http://link.springer.com/article/10.1186/s12934-017-0816-4
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