Up-regulation of the ATP-binding cassette transporter A1 inhibits hepatitis C virus infection.

Hepatitis C virus (HCV) establishes infection using host lipid metabolism pathways that are thus considered potential targets for indirect anti-HCV strategies. HCV enters the cell via clathrin-dependent endocytosis, interacting with several receptors, and virus-cell fusion, which depends on acidic p...

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Main Authors: Simone Bocchetta, Patrick Maillard, Mami Yamamoto, Claire Gondeau, Florian Douam, Stéphanie Lebreton, Sylvie Lagaye, Stanislas Pol, François Helle, Wanee Plengpanich, Maryse Guérin, Maryline Bourgine, Marie Louise Michel, Dimitri Lavillette, Philippe Roingeard, Wilfried le Goff, Agata Budkowska
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3960176?pdf=render
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