Molecular cloning, characterization, genomic organization and promoter analysis of the α1,6-fucosyltransferase gene (<it>fut8</it>) expressed in the rat hybridoma cell line YB2/0

<p>Abstract</p> <p>Background</p> <p>The rat hybridoma cell line YB2/0 appears a good candidate for the large-scale production of low fucose recombinant mAbs due to its lower expression of <it>fut8 </it>gene than other commonly used rodent cell lines. Howeve...

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Main Authors: Harduin-Lepers Anne, Bobowski Marie, Meurice Edwige, Teylaert Béatrice, Gaucher Christine, Fontayne Alexandre, Jorieux Sylvie, Delannoy Philippe
Format: Artigo
Jezik:Inglês
Izdano: BMC 2011-01-01
Serija:BMC Biotechnology
Online dostop:http://www.biomedcentral.com/1472-6750/11/1
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