Neuronal alarmin IL-1α evokes astrocyte-mediated protective signals: Effectiveness in chemotherapy-induced neuropathic pain

The distinction between glial painful and protective pathways is unclear and the possibility to finely modulate the system is lacking. Focusing on painful neuropathies, we studied the role of interleukin 1α (IL-1α), an alarmin belonging to the larger family of damage-associated molecular patterns en...

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Bibliografiska uppgifter
Huvudupphovsmän: Lorenzo Di Cesare Mannelli, Laura Micheli, Chiara Cervetto, Alessandra Toti, Elena Lucarini, Carmen Parisio, Manuela Marcoli, Carla Ghelardini
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2022-06-01
Serie:Neurobiology of Disease
Ämnen:
Neuropathic pain
Glia
Astrocyte
Interleukin 1
Neuroprotection
Glutamate
Länkar:http://www.sciencedirect.com/science/article/pii/S0969996122001085
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